The clinical management of LABC is complex and should be tailored to the individual patient, according to the biological features of the disease. IBC is an aggressive disease that progresses rapidly and carries a very grim prognosis. Accurate diagnosis is critically important, as multimodal therapy can significantly improve outcomes if instituted early enough. Patients with stage IIIB or IIIC disease who respond to primary chemotherapy should be treated until the response plateaus or to a maximum of six cycles minimum four cycles , after which several case series have demonstrated that locoregional control is improved [7—12]. The locoregional management of patients with stage IIIC disease who respond to chemotherapy is unclear and should be individualised. In the absence of evidence on this subgroup of patients, it is reasonable that they receive locoregional radiotherapy including nodal irradiation.
Standard Treatment vs. Clinical Trials - National Breast Cancer Foundation
Clinical Trials. Before selecting your treatment plan, you should first understand the difference between standard treatment and clinical trials. If a breast cancer clinical trial is an option for you, your doctor will explain the possible trade-offs with the trial treatment versus standard treatment. Together with your medical team, you will need to decide what treatment method is the best for you and your health. Other treatments may be appropriate for some women. Research studies clinical trials can be an option at all stages of breast cancer.
Skip to Content. Use the menu to see other pages. This section explains the types of treatments that are the standard of care for early-stage and locally advanced breast cancer. When making treatment plan decisions, you are encouraged to consider clinical trials as an option. A clinical trial is a research study that tests a new approach to treatment.
Explain the rationale for the multidisciplinary coordination of care for patients with locally advanced breast cancer. Identify the current standard of care for the treatment of locally advanced breast cancer. Locally advanced breast cancer remains a clinical challenge as the majority of patients with this diagnosis develop distant metastases despite appropriate therapy.